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当前位置: 首页 > 产品中心 > monoclonal_antibody > Abbiotec/TIP60 (3F9) Antibody/252714/0.1 ml
商品详细Abbiotec/TIP60 (3F9) Antibody/252714/0.1 ml
Abbiotec/TIP60 (3F9) Antibody/252714/0.1 ml
Abbiotec/TIP60 (3F9) Antibody/252714/0.1 ml
商品编号: 252714
品牌: Abbiotec LLC
市场价: ¥6780.00
美元价: 4068.00
产地: 美国(厂家直采)
公司:
产品分类: 单克隆抗体
公司分类: monoclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
HTATIP (HIV-1 Tat interacting protein TIP60) is ~60kDa protein. It belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4) is the primary building block of chromatin. In addition to the growing number of post-translational histone modifications regulating chromatin structure, cells can also exchange canonical histones with variant histones that can directly or indirectly modulate chromatin structure. There are five major variants of histone H2A: canonical H2A (most abundant), H2A.X, MacroH2A, H2ABbd and H2A.Z. Histone H2A.Z, the most conserved variant across species, functions as both a positive and negative regulator of transcription and is important for chromosome stability. Several homologous protein complexes, such as SWR-C, TIP60 and SRCAP (mammals) have been shown to catalyze the ATP-dependent exchange of H2A.Z for H2A in the nucleosome. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.
品牌介绍
Abbiotec坚信与我们的科学家,客户,合作者和分销商社区建立牢固而有意义的合作伙伴关系。我们通过研究合作与社区分享我们的想法,并通过有益于生命科学界的创新和有用的产品来回馈青睐。我们欢迎有关研究或产品创意的讨论,我们将努力为此类讨论提供最有利和最机密的环境。Abbiotec利用专有技术和特殊资源开发自己的产品,以实现高质量的生产和控制。我们还从其他合作伙伴(例如个人科学家,大学外发许可部门和其他生物技术公司)获得产品和想法的许可。被许可的技术或想法被开发为商业产品,并通过我们的营销和销售网络在全球范围内销售。