Abbiotec/NALP3 Antibody/254160/0.1 mg
商品编号:
254160
品牌:
Abbiotec LLC
市场价:
¥6820.00
美元价:
4092.00
产品分类:
单克隆抗体
公司分类:
monoclonal_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
NALP3, a member of Nod-like receptors, has a crucial role in inflammation and immunity and may be a proximal sensor of cellular stress and danger signals. NALP3 forms a caspase-1 activating molecular complex termed the inflammasome. The inflammasome allows activation of IL-1beta, the key player of the inflammation and fever. NALP3 gene encodes a pyrin like protein which contains a pyrin domain, a nucleotide binding site (NBS) domain, and a leucine rich repeat (LRR) motif. NALP3 protein interacts with apoptosis associated speck like protein containing a CARD and may function as an inducer of apoptosis and an activator of NF-kappaB signaling. Defects in NALP3 have been associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID).
品牌介绍
Abbiotec坚信与我们的科学家,客户,合作者和分销商社区建立牢固而有意义的合作伙伴关系。我们通过研究合作与社区分享我们的想法,并通过有益于生命科学界的创新和有用的产品来回馈青睐。我们欢迎有关研究或产品创意的讨论,我们将努力为此类讨论提供最有利和最机密的环境。Abbiotec利用专有技术和特殊资源开发自己的产品,以实现高质量的生产和控制。我们还从其他合作伙伴(例如个人科学家,大学外发许可部门和其他生物技术公司)获得产品和想法的许可。被许可的技术或想法被开发为商业产品,并通过我们的营销和销售网络在全球范围内销售。
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